Skip to main content

DNA Analysis and Hematologic Cancer

Feb 01, 2015 01:11PM, Published by Jennifer Neys, Categories: Health+Wellness


Kasra Karamlou, MD



By Kasra Karamlou, MD

It is known that cancer is developed through multiple mutations in the body, and in some cancers those early mutations cause clonal expansions. It was hypothesized that duplication of specific mutated genes could be identified as predecessors to hematologic cancers.

A study published November 26, 2014, with the New England Journal of Medicine shows an interesting promise toward detection of hematologic cancers prior to onset of clinically apparent symptoms through DNA sequencing. The study was conducted on 12,380 persons who received complete DNA sequencing and then were followed up for 2-7 years.

It was found that four genes resulted with higher numbers of mutations than others. These genes were identified as “drivers” of somatic mutation, meaning that they contribute to production of cells arising from a single cell. Data shows that as individuals age, they are more likely to possess gene drivers that may be a contributor to hematologic cancer. It was also found that as the age of the individual increases, so does the amount of mutations found.

Upon observation it was apparent that the same driver gene mutations that were detected in participants were present in individuals with hematologic cancers. These genes can be mutated and leave individuals un-symptomatic for long periods of time before perhaps cooperating events attribute to hematological cancer. 

While currently there are no interventions available for individuals who have a slightly elevated risk of hematologic cancer, and testing positive for these mutated genes does not warrant a diagnosis of such, it is hoped that strategies may be developed for eventual early detection and prevention of the hematologic cancer and other diseases so risks can be calculated with DNA screening. 

Dr. Karamlou is a Medical Oncologist and Hematologist with Diablo Valley Oncology in Pleasant Hill.  He specializes in treating hematologic malignances and benign hematology. To hear more on leukemia, lymphoma, and myeloma, join Dr. Karamlou and Dr. Robles for a free event focusing on the unique issues of patients with blood cancer. They will discuss and share exciting new research, treatments, and therapies recently announced at the American Society of Hematology’s annual meeting. Q & A session to follow. February 11, 2015, 6:30pm at Walnut Creek Library’s Oak Room, 1644 N. Broadway, Walnut Creek, CA 94596. For more information, visit dvohmg.com or call 925-677-5041.



It looks like we don't have any events for this date. You can always add an event.

  • Happy Hour & A Half

    08/18/2017
    04:30PM — 06:00PM

    Live music No cover charge Beverage discount Doors open 4:00


  • THE JESSE BREWSTER BAND

    08/18/2017
    08:00PM — 10:00PM

    "Alt-Country, Folk Rock" Jesse Brewster - guitar/ vocals Dave Sampson - guitar Ryan Low - dr...


  • The Valley Beer Tour

    08/20/2017
    11:30AM — 04:00PM

    Livermore has an abundance of wineries now being complemented by a growing craft beer scene. Wit...


  • Rockridge Ice Cream & Gelato Tour

    08/20/2017
    03:00PM — 04:00PM

    Satisfy your sweet tooth this this one-hour guided walking tour that helps kids of all ages explo...


  • THE LOWELL TRIO

    08/20/2017
    04:00PM — 06:00PM

    "Classical" With members of the San Francisco Opera Orchestra The Lowell Trio annual Summer...


It looks like we don't have any events for this date. You can always add an event.

It looks like we don't have any events for this date. You can always add an event.

  • Volunteer Gardening

    08/23/2017
    09:00AM — 12:00PM

    It takes a lot of effort to maintain six acres of lush garden space, and as a small, nonprofit or...


  • Community Garden Swap Meet

    08/23/2017
    12:00PM — 12:30PM

    Have an excess harvest of yummy and pretty things from your home garden? Bring fruits, vegetables...


  • MONTHLY MOSTLY BLUEGRASS EXTRAVAGANZA

    08/23/2017
    07:30PM — 10:00PM

    Hosted by the Armando's House Bluegrass Band Bruce Campbell - bass Rick Horlick - mandolin L...


  • Happy Hour & A Half

    08/18/2017
    04:30PM — 06:00PM

    Live music No cover charge Beverage discount Doors open 4:00


  • THE JESSE BREWSTER BAND

    08/18/2017
    08:00PM — 10:00PM

    "Alt-Country, Folk Rock" Jesse Brewster - guitar/ vocals Dave Sampson - guitar Ryan Low - dr...


  • Public Art Walking Tours in Walnut Creek

    08/19/2017
    11:00AM — 12:00PM

    Enjoy a one hour, docent-led walking tour of Walnut Creek's wonderful downtown public art collect...


  • Rockridge Ice Cream & Gelato Tour

    08/19/2017
    03:00PM — 04:00PM

    Satisfy your sweet tooth this this one-hour guided walking tour that helps kids of all ages explo...


  • Satisfy your sweet tooth this this one-hour guided walking tour that helps kids of all ages - and...


  • Jazz Experience at the Lesher Center

    08/19/2017
    05:00PM — 07:00PM

    Jazz Experience at the Lesher Center, presented by the Diablo Regional Arts Association, will ret...


  • "In Pursuit of Silence"

    08/19/2017
    07:30PM — 09:30PM

    A unique "summer escape" film. Filmmaker Patrick Shen explores silence and the impact of noise in...


  • THE TERRY HANCK BAND

    08/19/2017
    08:00PM — 10:00PM

    "Blues and R&B" Terry Hanck - sax/ vocals Johnny”Cat” Soubrand - guitar Butch Cousins - drum...


  • Jazz Experience at the Lesher Center

    08/19/2017
    08:00PM — 10:00PM

    Jazz Experience at the Lesher Center, presented by the Diablo Regional Arts Association, will ret...


  • The Valley Beer Tour

    08/20/2017
    11:30AM — 04:00PM

    Livermore has an abundance of wineries now being complemented by a growing craft beer scene. Wit...


  • Rockridge Ice Cream & Gelato Tour

    08/20/2017
    03:00PM — 04:00PM

    Satisfy your sweet tooth this this one-hour guided walking tour that helps kids of all ages explo...


  • THE LOWELL TRIO

    08/20/2017
    04:00PM — 06:00PM

    "Classical" With members of the San Francisco Opera Orchestra The Lowell Trio annual Summer...


  • Volunteer Gardening

    08/23/2017
    09:00AM — 12:00PM

    It takes a lot of effort to maintain six acres of lush garden space, and as a small, nonprofit or...


  • Community Garden Swap Meet

    08/23/2017
    12:00PM — 12:30PM

    Have an excess harvest of yummy and pretty things from your home garden? Bring fruits, vegetables...


  • MONTHLY MOSTLY BLUEGRASS EXTRAVAGANZA

    08/23/2017
    07:30PM — 10:00PM

    Hosted by the Armando's House Bluegrass Band Bruce Campbell - bass Rick Horlick - mandolin L...


  • FPHE Green Team meeting - new members wanted!

    08/24/2017
    04:00PM — 05:00PM

    We encourage and support all things Green in Pleasant Hill schools, including school gardens, sal...


  • QUINN DEVEAUX

    08/24/2017
    08:00PM — 10:00PM

    “Soul Blues” Joe Lewis - electric bass Quinn DeVeaux - guitar/vocals Andrew Maguire - Drums ...


  • Happy Hour & A Half

    08/25/2017
    04:30PM — 06:00PM

    Live music with KYLE JESTER No cover charge Beverage discount Doors open 4:00


  • Walnut Creek Movies Under the Stars: Grease

    08/25/2017
    06:30PM — 10:00PM

    Bring your family and enjoy this FREE outdoor moving screening! Bring a picnic or enjoy dinner at...


  • THE MAD MAGGIES

    08/25/2017
    08:00PM — 10:00PM

    "Ska, Zydeco and Folk Rock" Maggie Martin - accordion/ vocals Johny Blood - tuba Ray Rernand...


  • Eat Stay Love Lafayette Food Tour

    08/26/2017
    11:00AM — 01:00PM

    Green Hills. Great Schools. Good-tasting Eats. Our Eat – Stay – Love Lafayette food tour is a tw...


  • Rockridge Ice Cream & Gelato Tour

    08/26/2017
    03:00PM — 04:00PM

    Satisfy your sweet tooth this this one-hour guided walking tour that helps kids of all ages explo...


  • Jazz Experience at the Lesher Center

    08/26/2017
    05:00PM — 07:00PM

    Jazz Experience at the Lesher Center, presented by the Diablo Regional Arts Association, will ret...


  • PETER ANASTOS & ITER + GREEK JAZZ

    08/26/2017
    08:00PM — 10:30PM

    "Post Bop Original Jazz" Peter Anastos - trumpet Jodi Durst - bass Heikki Koskonen - piano ...


  • Jazz Experience at the Lesher Center

    08/26/2017
    08:00PM — 10:00PM

    Jazz Experience at the Lesher Center, presented by the Diablo Regional Arts Association, will ret...


  • Rockridge Ice Cream & Gelato Tour

    08/27/2017
    03:00PM — 04:00PM

    Satisfy your sweet tooth this this one-hour guided walking tour that helps kids of all ages explo...


  • THE SUNDAY PAPER

    08/27/2017
    04:00PM — 07:00PM

    "Bay Area Funk" With former and current members of Tower Of Power, Cold Blood, Sly & The Famil...


  • Volunteer Gardening

    08/30/2017
    09:00AM — 12:00PM

    It takes a lot of effort to maintain six acres of lush garden space, and as a small, nonprofit or...


  • Community Garden Swap Meet

    08/30/2017
    12:00PM — 12:30PM

    Have an excess harvest of yummy and pretty things from your home garden? Bring fruits, vegetables...


  • Plant Spotlight Classes

    08/30/2017
    12:30PM — 01:00PM

    Bring a sketchbook or notebook to The Gardens at Heather Farm as we spotlight one special plant i...


  • Join us for an Event Marketing Workshop on how to manage events big and small. The event is happe...


  • THE RAY CHARLES PROJECT

    08/31/2017
    08:00PM — 10:00PM

    Tony Lindsey - vocals Glenn Walters - vocals Chris Cain - guitar David K. Mathews - organ Dwa...


  • Happy Hour & A Half

    09/01/2017
    04:30PM — 06:00PM

    Live music with SIN SILVER No cover charge Beverage discount Doors open 4:00


  • LITTLE ROGER & THE GOOSEBUMPS

    09/01/2017
    08:00PM — 10:00PM

    "Pop Rock" Roger Clark - guitar/ vocals David Seabury - drums John Seabury - bass Donn Spin...


  • The Valley Beer Tour

    09/02/2017
    11:30AM — 04:00PM

    Livermore has an abundance of wineries now being complemented by a growing craft beer scene. Wit...


  • "Anything Goes" art gallery opening

    09/02/2017
    02:00PM — 06:30PM

    Art show opening ‘Anything Goes’ at the Raquel Amaral Studio/Gallery on September 2nd, 2017 2...


  • Rockridge Ice Cream & Gelato Tour

    09/02/2017
    03:00PM — 04:00PM

    Satisfy your sweet tooth this this one-hour guided walking tour that helps kids of all ages explo...


  • LAVAY SMITH & HER RED HOT SKILLIT LICKERS

    09/02/2017
    08:00PM — 10:00PM

    "Red, White & Blues: A Celebration Of America's Cities, States & Regions" Lavay Smith - vocal...


  • Rockridge Ice Cream & Gelato Tour

    09/03/2017
    03:00PM — 04:00PM

    Satisfy your sweet tooth this this one-hour guided walking tour that helps kids of all ages explo...


  • MICHELE'S SUNNY SUNDAY BIRTHDAY BASH

    09/03/2017
    04:00PM — 07:00PM

    Featuring…. Yours Truly Michele (Michele Kappel) "She’s a celebration. No matter your mood, yo...


  • BLUES SHOWCASE

    09/04/2017
    07:30PM — 10:00PM

    Al Smith Band Memphis Blues Project Harrison Flynn and Friends Barry Craig and Friends


  • Volunteer Gardening

    09/06/2017
    09:00AM — 12:00PM

    It takes a lot of effort to maintain six acres of lush garden space, and as a small, nonprofit or...


  • DREAM POSSE

    09/07/2017
    08:00PM — 10:00PM

    “Eclectic Country Rock” CD Release Party! Kiki Stack – vocals Katy Lawrence – vocals/ viol...


 

 

 

July 2017

 

 

Oasis Veterinary Pet Adoption Connection

 

Loading Family Features Content Widget
Loading Family Features Article

 

Interested in advertising or becoming a community sponsor? Contact us at 925-335-6397 or email us at info@ourcommunityfocus.com